兔抗HCK(Phospho-Tyr521) 多克隆抗体

Background:

The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. [provided by RefSeq, Feb 2010]

Applications:

WB

Name of antibody:

HCK(Phospho-Tyr521)

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 521(E-S-Q(p)-Y-Q) derived from Human HCK .

Full name:

HCK proto-oncogene, Src family tyrosine kinase

Synonyms：

JTK9; p59Hck; p61Hck

SwissProt:

P08631

WB Predicted band size:

60 kDa

WB Positive control:

Jurkat cells lysates

WB Recommended dilution:

500-1000