兔抗CARD11多克隆抗体

Background:

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation.

Applications:

ELISA, IHC

Name of antibody:

CARD11

Immunogen:

Fusion protein of human CARD11

Full name:

caspase recruitment domain family, member 11

Synonyms：

PPBL; BENTA; BIMP3; IMD11; CARMA1

SwissProt:

Q9BXL7

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human breast cancer and human liver cancer

IHC Recommend dilution:

50-200