| Background: | Nucleosome-destabilizing factor that is recruited to genes during transcriptional activation (PubMed:29759984). Facilitates Pol II transcription through nucleosomes (PubMed:29759984). Binds DNA (in vitro) (PubMed:29759984). Recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3) (PubMed:20850016). Promotes KDM1B demethylase activity (PubMed:23260659). Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac) by EP300 (PubMed:29759984). Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling (PubMed:16352664). Indirectly promotes phosphorylation of MAPK14 and activation of ATF2 (PubMed:16352664). The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6 (PubMed:16352664). Putative oxidoreductase (PubMed:23260659). | 
| Applications: | ELISA, WB | 
| Name of antibody: | GLYR1 | 
| Immunogen: | Synthetic peptide of human GLYR1 | 
| Full name: | glyoxylate reductase 1 homolog | 
| Synonyms: | NP60; BM045; HIBDL; N-PAC | 
| SwissProt: | Q49A26 | 
| ELISA Recommended dilution: | 2000-5000 | 
| WB Predicted band size: | 61 kDa | 
| WB Positive control: | Hela, Jurkat, K562 and HUVEC cells | 
| WB Recommended dilution: | 500-2000 | 

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