小鼠抗BCAT1单克隆抗体

Background:

This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq].

Applications:

WB, IHC

Name of antibody:

BCAT1

Immunogen:

Fusion protein of human BCAT1

Full name:

branched chain amino-acid transaminase 1, cytosolic (BCAT1), transcript variant 1

Synonyms:

BCATC; BCT1; ECA39; MECA39; PNAS121; PP18

SwissProt:

P54687

IHC positive control:

human lymphoma tissue and human tonsil tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

43 kDa

WB Positive control:

Human testis tissue, Human omentum tissue, Human uterus tissue, Human breast tissue, Human brain tissue, Human thyroid gland tissue lysates

WB Recommended dilution:

500-2000