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021-54845833/15800441009
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Background: |
TPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin-induced microbutule assembly during M phase. Aurora-A kinase associates with TPX2 at the spindle apparatus and may regulate TPX2 via phosphorylation during the spindle assembly. TPX2 appears to play a structural role in spindle formation. TPX2 activates Eg2 in a microtubule-dependent manner by stimulating the phosphorylation and kinase activity of Eg2. |
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Applications: |
ELISA, WB |
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Name of antibody: |
TPX2 |
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Immunogen: |
Fusion protein of human TPX2 |
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Full name: |
TPX2, microtubule-associated |
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Synonyms： |
DIL2; p100; DIL-2; HCTP4; FLS353; HCA519; REPP86; C20orf1; C20orf2; GD:C20orf1 |
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SwissProt: |
Q9ULW0 |
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ELISA Recommended dilution: |
2000-5000 |
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WB Predicted band size: |
86 kDa |
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WB Positive control: |
K562 and A431 cells |
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WB Recommended dilution: |
500-2000 |
