兔抗CYP2E1多克隆抗体

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

Applications:

ELISA, WB, IHC

Name of antibody:

CYP2E1

Immunogen:

Fusion protein of human CYP2E1

Full name:

cytochrome P450, family 2, subfamily E, polypeptide 1

Synonyms：

CPE1; CYP2E; P450-J; P450C2E

SwissProt:

P05181

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

57 kDa

WB Positive control:

Mouse liver tissue

WB Recommended dilution:

500-2000