兔抗IFITM1多克隆抗体

Background:

The IFITM family of proteins are transmembrane proteins so named because their expression is IFN-inducible. IFITM proteins have been found upregulated in human colorectal carcinomas. Both mouse IFITM1 (also known as CD225) and IFITM3 demonstrate expression on the cell surfaces of primordial germ cells in a developmentally-regulated manner. They presumably modulate cell adhesion and influence cell differentiation. IFITM1 activity is required for primordial germ cell transit, and IFITM1 acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm.

Applications:

ELISA, WB, IHC

Name of antibody:

IFITM1

Immunogen:

Synthetic peptide of human IFITM1

Full name:

interferon induced transmembrane protein 1

Synonyms：

9-27; CD225; IFI17; LEU13; DSPA2a

SwissProt:

P13164

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer and human ovarian cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

14 kDa

WB Positive control:

Hela and NIH/3T3 cell

WB Recommended dilution:

500-2000