兔抗ANAPC5多克隆抗体

Background:

This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

ANAPC5

Immunogen:

Fusion protein of human ANAPC5

Full name:

anaphase promoting complex subunit 5

Synonyms：

APC5

SwissProt:

Q9UJX4

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human thyroid cancer and human liver cancer

IHC Recommend dilution:

50-200