兔抗CAV3多克隆抗体

Background:

This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

Applications:

ELISA, WB, IHC

Name of antibody:

CAV3

Immunogen:

Synthetic peptide of human CAV3

Full name:

caveolin 3

Synonyms:

LQT9; VIP21; LGMD1C; VIP-21

SwissProt:

P56539

IHC positive control:

Human gastric cancer and human thyroid cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

17 kDa

WB Positive control:

Human fetal muscle tissue

WB Recommended dilution:

500-2000