小鼠抗ALPP单克隆抗体

Background:

The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells.

Applications:

WB

Name of antibody:

ALPP

Immunogen:

Fusion protein of human ALPP

Full name:

alkaline phosphatase, placental

Synonyms:

ALP; PALP; PLAP; PLAP-1

SwissProt:

P05187

WB Predicted band size:

58 kDa

WB Positive control:

HepG2, Hela, CHO-K1 and CHO-K1 transfected pcDNA3.1-HA-PLAP cell lysates

WB Recommended dilution:

1000-5000