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中文名称： 兔抗MAP3K8(Ab-400) 多克隆抗体
英文名称：Anti-MAP3K8(Ab-400) rabbit polyclonal antibody
别 名： COT; EST; ESTF; TPL2; MEKK8; Tpl-2; c-COT
相关类别： 一抗
储 存： 冷冻（-20℃） 避光
宿 主： Rabbit
抗 原： MAP3K8(Ab-400)
反应种属：Human
标 记 物： Unconjugate
克隆类型：rabbit polyclonal
技术规格
Background:
This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus.
Applications:
WB, IHC
Name of antibody:
MAP3K8(Ab-400)
Immunogen:
Synthesized non-phosphopeptide derived from human MAP3K8 around the phosphorylation site of serine 400 (C-Q-S(p)-L-D).
Full name:
mitogen-activated protein kinase kinase kinase 8
Synonyms：
COT; EST; ESTF; TPL2; MEKK8; Tpl-2; c-COT
SwissProt:
P41279
IHC positive control:
Human brain tissue
IHC Recommend dilution:
50-100
WB Predicted band size:
53 kDa
WB Positive control:
COLO cells treated with Insulin (0.01U/ml, 15mins) lysate
WB Recommended dilution:
500-3000
