| Background: | The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses. Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. | 
| Applications: | ELISA, WB, IHC | 
| Name of antibody: | TRAFD1 | 
| Immunogen: | Fusion protein of human TRAFD1 | 
| Full name: | TRAF-type zinc finger domain containing 1 | 
| Synonyms: | FLN29 | 
| SwissProt: | O14545 | 
| ELISA Recommended dilution: | 1000-2000 | 
| IHC positive control: | Human thyroid cancer and human brain | 
| IHC Recommend dilution: | 25-100 | 
| WB Predicted band size: | 65 kDa | 
| WB Positive control: | Mouse spleen tissue | 
| WB Recommended dilution: | 200-1000 | 
	
	
 
 
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