兔抗BRSK2多克隆抗体

Background:

BRSK2 (BR serine/threonine kinase 2), also known as SAD1, STK29 or PEN11B, is a 736 amino acid protein that contains one protein kinase domain and is preferentially expressed in brain and testis. One of several members of the Ser/Thr protein kinase family, BRSK2 uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be involved in microtubule assembly, neuronal polarization and synaptic development. Additionally, BRSK2 may function as an autoantigen involved in small-cell lung cancer-associated limbic encephalitis. Five isoforms of BRSK2 exist due to alternative splicing events.

Applications:

ELISA, IHC

Name of antibody:

BRSK2

Immunogen:

Synthetic peptide of human BRSK2

Full name:

BR serine/threonine kinase 2

Synonyms:

SAD1; SADA; STK29; PEN11B; C11orf7

SwissProt:

Q8IWQ3

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human brain

IHC Recommend dilution:

40-200