兔抗TIGAR多克隆抗体

Background:

This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis.

Applications:

ELISA, WB, IHC

Name of antibody:

TIGAR

Immunogen:

Synthetic peptide of human TIGAR

Full name:

TP53 induced glycolysis regulatory phosphatase

Synonyms：

FR2BP; C12orf5

SwissProt:

Q9NQ88

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human cervical cancer and Human breast cancer

IHC Recommend dilution:

100-300

WB Predicted band size:

30 kDa

WB Positive control:

Human normal liver tissue

WB Recommended dilution:

200-1000