兔抗ALAS1多克隆抗体

Background:

This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Applications:

ELISA, IHC

Name of antibody:

ALAS1

Immunogen:

Fusion protein of human ALAS1

Full name:

aminolevulinate, delta-, synthase 1

Synonyms：

ALAS; MIG4; ALAS3; ALASH

SwissProt:

P13196

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human breast cancer and human thyroid cancer

IHC Recommend dilution:

25-100