兔抗FGF3多克隆抗体

Background:

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation.

Applications:

ELISA, WB, IHC

Name of antibody:

FGF3

Immunogen:

Synthetic peptide of human FGF3

Full name:

fibroblast growth factor 3

Synonyms:

INT2; HBGF-3

SwissProt:

P11487

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and human esophagus cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

27 kDa

WB Positive control:

Rat liver tissue lysate

WB Recommended dilution:

200-1000