兔抗ARHGEF6多克隆抗体

Background:

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation.

Applications:

ELISA, IHC

Name of antibody:

ARHGEF6

Immunogen:

Synthetic peptide of human ARHGEF6

Full name:

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

Synonyms：

PIXA; COOL2; MRX46; Cool-2; alphaPIX; alpha-PIX

SwissProt:

Q15052

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human lung cancer

IHC Recommend dilution:

50-200