兔抗ZBTB44多克隆抗体

Background:

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 44 (ZBTB44), also known as BTBD15, is a 570 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB44 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB44 functions as a transcription regulator. Four isoforms of ZBTB44 have been identified.

Applications:

ELISA, IHC

Name of antibody:

ZBTB44

Immunogen:

Fusion protein of human ZBTB44

Full name:

zinc finger and BTB domain containing 44

Synonyms:

BTBD15; ZNF851; HSPC063

SwissProt:

Q8NCP5

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and human colorectal cancer

IHC Recommend dilution:

30-150