| Background: | Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | 
| Applications: | ELISA, IHC | 
| Name of antibody: | KARS1 | 
| Immunogen: | Fusion protein of human KARS1 | 
| Full name: | lysyl-tRNA synthetase 1 | 
| Synonyms: | KRS; KARS; KARS2; CMTRIB; DFNB89 | 
| SwissProt: | Q15046 | 
| IHC positive control: | Human brain and Human ovarian cancer | 
| IHC Recommend dilution: | 50-200 | 

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