兔抗ACKR2多克隆抗体

Background:

This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.

Applications:

ELISA, WB, IHC

Name of antibody:

ACKR2

Immunogen:

Synthetic peptide of human ACKR2

Full name:

atypical chemokine receptor 2

Synonyms:

D6; hD6; CCR9; CCBP2; CCR10; CMKBR9

SwissProt:

O00590

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

43 kDa

WB Positive control:

Human placenta tissue lysate

WB Recommended dilution:

200-1000