兔抗SRC多克隆抗体

Background:

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

SRC

Immunogen:

Fusion protein of human SRC

Full name:

V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)

Synonyms：

ASV; SRC1; c-SRC; p60-Src

SwissProt:

P12931

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human lymphoma and Human colon cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

60 kDa

WB Positive control:

PC3 cells

WB Recommended dilution:

200-1000