兔抗CNGA4多克隆抗体

Background:

Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.

Applications:

ELISA, WB, IHC

Name of antibody:

CNGA4

Immunogen:

Synthetic peptide of human CNGA4

Full name:

cyclic nucleotide gated channel alpha 4

Synonyms:

CNG4; CNG5; CNCA2; CNG-4; CNGB2; OCNC2; OCNCb; OCNCBETA

SwissProt:

Q8IV77

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer; Human brain

IHC Recommend dilution:

20-100

WB Predicted band size:

66 kDa

WB Positive control:

Human cerebella tissue and Human cerebrum tissue lysates

WB Recommended dilution:

200-1000