兔抗EPOR(Phospho-Tyr368) 多克隆抗体

Background:

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival.

Applications:

WB

Name of antibody:

EPOR(Phospho-Tyr368)

Immunogen:

Peptide sequence around phosphorylation site of Tyrosine 368 (D-T-Y(p)-L-V) derived from Human Epo-R.

Full name:

erythropoietin receptor

Synonyms：

erythropoietin receptor

SwissProt:

P19235

WB Predicted band size:

55 kDa

WB Positive control:

K562 cells lysates

WB Recommended dilution:

500-1000