兔抗ABCC4多克隆抗体

Background:

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

ABCC4

Immunogen:

Synthetic peptide of human ABCC4

Full name:

ATP binding cassette subfamily C member 4

Synonyms:

MRP4; MOATB; MOAT-B

SwissProt:

O15439

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

25-100