兔抗PMP22多克隆抗体

Background:

This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, WB, IHC

Name of antibody:

PMP22

Immunogen:

Synthetic peptide of human PMP22

Full name:

peripheral myelin protein 22

Synonyms:

DSS; GAS3; HNPP; CMT1A; CMT1E; GAS-3; Sp110; HMSNIA

SwissProt:

Q01453

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer

IHC Recommend dilution:

20-100

WB Predicted band size:

18 kDa

WB Positive control:

Human cerebrum tissue，A172 cell，Mouse lung tissue，293T cell，231 cell，Mouse liver tissue，Mouse brain tissue lysates

WB Recommended dilution:

200-1000