小鼠抗ATIC单克隆抗体

Background:

This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq].

Applications:

WB, FC

Name of antibody:

ATIC

Immunogen:

Fusion protein of human ATIC

Full name:

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC)

Synonyms:

AICAR; AICARFT; HEL-S-70p; IMPCHASE; PURH

SwissProt:

P31939

WB Predicted band size:

65 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, COS7, MDCK, PC12, MCF-7 cell lysates

WB Recommended dilution:

500-2000