兔抗E2F3多克隆抗体

Background:

This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

E2F3

Immunogen:

Synthetic peptide of human E2F3

Full name:

E2F transcription factor 3

Synonyms:

E2F-3

SwissProt:

O00716

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human breast cancer

IHC Recommend dilution:

25-100