兔抗CD276多克隆抗体

Background:

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

CD276

Immunogen:

Synthetic peptide of human CD276

Full name:

CD276 molecule

Synonyms:

B7H3; B7-H3; B7RP-2; 4Ig-B7-H3

SwissProt:

Q5ZPR3

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

57 kDa

WB Positive control:

293T，LNCAP，231 and PC-3 cell lysates

WB Recommended dilution:

200-1000