兔抗COX4I2多克隆抗体

Background:

Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation.

Applications:

ELISA, IHC

Name of antibody:

COX4I2

Immunogen:

Synthetic peptide of human COX4I2

Full name:

cytochrome c oxidase subunit 4I2

Synonyms:

COX4; COX4B; COX4-2; COX4L2; COXIV-2; dJ857M17.2

SwissProt:

Q96KJ9

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

25-100