兔抗DNM1L多克隆抗体

Background:

This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

Applications:

ELISA, WB, IHC

Name of antibody:

DNM1L

Immunogen:

Fusion protein of human DNM1L

Full name:

dynamin 1 like

Synonyms:

DLP1; DRP1; DVLP; EMPF; OPA5; EMPF1; DYMPLE; HDYNIV

SwissProt:

O00429

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human colorectal cancer

IHC Recommend dilution:

200-300

WB Predicted band size:

82 kDa

WB Positive control:

Raji cell and Mouse brain tissue lysates

WB Recommended dilution:

500-2000