兔抗ACTG1多克隆抗体

Background:

Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, WB

Name of antibody:

ACTG1

Immunogen:

Fusion protein of human ACTG1

Full name:

actin, gamma 1

Synonyms：

ACT, ACTG, BRWS2, DFNA20, DFNA26

SwissProt:

P63261

ELISA Recommended dilution:

1000-5000

WB Predicted band size:

42 kDa

WB Positive control:

Human liver cancer tissue

WB Recommended dilution:

200-1000