兔抗FBXO31多克隆抗体

Background:

This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

FBXO31

Immunogen:

Synthetic peptide of human FBXO31

Full name:

F-box protein 31

Synonyms:

FBX14; Fbx31; MRT45; FBXO14; pp2386

SwissProt:

Q5XUX0

ELISA Recommended dilution:

500-1000

IHC positive control:

Human liver cancer and Human colorectal cancer

IHC Recommend dilution:

25-50