兔抗AMZ2多克隆抗体

Background:

AMZ2 (archaelysin family metallopeptidase 2), also known as archaemetzincin-2 or archeobacterial metalloproteinase-like protein 2, is a 360 amino acid protein belonging to the peptidase M54 family. Encoded by a gene that maps to human chromosome 17q24.2, AMZ2 is predominantly expressed in heart and testis. AMZ2 is also expressed in kidney, liver, pancreas, lung, brain and placenta, and in fetal tissues such as kidney, liver, lung and brain. AMZ2 participates in metal ion binding and functions as a zinc metalloprotease. AMZ2 is inhibited by both general metalloprotease inhibitors o-phenanthroline and batimastat. Exhibiting aminopeptidase activity, AMZ2 acts against Angiotensin in vitro, but does not hydrolyze either Neurogranin or Angiotensin.

Applications:

ELISA, IHC

Name of antibody:

AMZ2

Immunogen:

Fusion protein of human AMZ2

Full name:

archaelysin family metallopeptidase 2

SwissProt:

Q86W34

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human thyroid cancer and human liver cancer

IHC Recommend dilution:

50-200