兔抗ATP6AP1多克隆抗体

Background:

This gene encodes a component of a multisubunit enzyme (1 mDa MW) that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene is approximately 45 kD and may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules.

Applications:

WB

Name of antibody:

ATP6AP1

Immunogen:

Fusion protein of human ATP6AP1

Full name:

ATPase, H+ transporting, lysosomal accessory protein 1

Synonyms：

ATP6AP1; 16A; ATP6IP1; ATP6S1; Ac45; CF2; MGC129781; VATPS1; XAP-3; XAP3

SwissProt:

Q15904

WB Predicted band size:

52 kDa

WB Positive control:

HeLa and HepG2 cells

WB Recommended dilution:

500-2000