兔抗BMP3多克隆抗体

Background:

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands.

Applications:

ELISA, WB

Name of antibody:

BMP3

Immunogen:

Fusion protein of human BMP3

Full name:

bone morphogenetic protein 3

Synonyms:

BMP-3A

SwissProt:

P12645

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

53 kDa

WB Positive control:

NIH/3T3 cell lysate

WB Recommended dilution:

200-1000