兔抗CACNA1D多克隆抗体

Background:

Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

CACNA1D

Immunogen:

Synthetic peptide of human CACNA1D

Full name:

calcium channel, voltage-dependent, L type, alpha 1D subunit

Synonyms：

CACH3; CACN4; PASNA; SANDD; Cav1.3; CCHL1A2; CACNL1A2

SwissProt:

Q01668

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human brain and Human thyroid cancer

IHC Recommend dilution:

50-200