小鼠抗LZTS1单克隆抗体

Background:

This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.

Applications:

WB

Name of antibody:

LZTS1

Immunogen:

Fusion protein of human LZTS1

Full name:

leucine zipper tumor suppressor 1

Synonyms:

F37; FEZ1

SwissProt:

Q9Y250

WB Predicted band size:

67 KD

WB Positive control:

Jurkat cell lysate

WB Recommended dilution:

200-1000