兔抗CYP2D6多克隆抗体

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine and propafenone, both anti-arrythmic drugs; and amitryptiline, an anti-depressant.

Applications:

ELISA, WB, IHC

Name of antibody:

CYP2D6

Immunogen:

Synthetic peptide of human CYP2D6

Full name:

cytochrome P450, family 2, subfamily D, polypeptide 6

Synonyms:

CPD6; CYP2D; CYP2DL1; CYPIID6; P450C2D; P450DB1; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; P450-DB1

SwissProt:

P10635

IHC positive control:

Human gastric cancer and human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

56 kDa

WB Positive control:

K562 cells

WB Recommended dilution:

200-1000