兔抗CREB1(Phospho-Ser142) 多克隆抗体

Background:

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

Applications:

WB, IHC

Name of antibody:

CREB1(Phospho-Ser142)

Immunogen:

Peptide sequence around phosphorylation site of serine 142(D-L-S(p)-S-D) derived from Human CREB.

Full name:

cAMP responsive element binding protein 1

Synonyms：

CREB

SwissProt:

P16220

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

37 kDa

WB Positive control:

293 cells lysates treated with calf intestinal phosphatase (CIP)

WB Recommended dilution:

500-1000