兔抗UBE2E3多克隆抗体

Background:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

UBE2E3

Immunogen:

Fusion protein of human UBE2E3

Full name:

ubiquitin conjugating enzyme E2E 3

Synonyms:

UBCH9; UbcM2

SwissProt:

Q969T4

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer and human esophagus cancer

IHC Recommend dilution:

30-150