兔抗PIM1多克隆抗体

Background:

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.

Applications:

ELISA, IHC

Name of antibody:

PIM1

Immunogen:

Fusion protein of human PIM1

Full name:

pim-1 oncogene

Synonyms：

PIM

SwissProt:

P11309

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human liver cancer and human thyroid cancer

IHC Recommend dilution:

50-200