兔抗SLC22A17多克隆抗体

Background:

Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.

Applications:

ELISA, WB, IHC

Name of antibody:

SLC22A17

Immunogen:

Synthetic peptide of human SLC22A17

Full name:

solute carrier family 22, member 17

Synonyms：

BOCT, BOIT, 24p3R, NGALR, hBOIT, NGALR2, NGALR3

SwissProt:

Q8WUG5

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human esophagus cancer and Human cervical cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

56 kDa

WB Positive control:

Human esophagus cancer tissue

WB Recommended dilution:

500-2000