兔抗ADM多克隆抗体

Background:

Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element.

Applications:

ELISA, IHC

Name of antibody:

ADM

Immunogen:

Synthetic peptide of human ADM

Full name:

adrenomedullin

Synonyms：

AM

SwissProt:

P35318

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human breast cancer and Human cervical cancer

IHC Recommend dilution:

25-100