兔抗FMR1多克隆抗体

Background:

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Applications:

ELISA, IHC

Name of antibody:

FMR1

Immunogen:

Fusion protein of human FMR1

Full name:

fragile X mental retardation 1

Synonyms：

POF; FMRP; POF1; FRAXA

SwissProt:

Q06787

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-200