小鼠抗NFKBIE单克隆抗体

Background:

The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus.

Applications:

WB

Name of antibody:

NFKBIE

Immunogen:

Fusion protein of human NFKBIE

Full name:

NFKB inhibitor epsilon

Synonyms:

IKBE

SwissProt:

O00221

WB Predicted band size:

53 KD

WB Positive control:

Jurkat, Hela and A375 cell lysates

WB Recommended dilution:

500-2000