小鼠抗ROR2单克隆抗体

Background:

The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.

Applications:

WB, IHC

Name of antibody:

ROR2

Immunogen:

Fusion protein of human ROR2

Full name:

receptor tyrosine kinase like orphan receptor 2

Synonyms:

BDB; BDB1; NTRKR2

SwissProt:

Q01974

IHC positive control:

Human prostate cancer and Human ovarian cancer

IHC Recommend dilution:

200-500

WB Predicted band size:

105 KD

WB Positive control:

Hela, K562, HepG2 and SH-SY5Y cell lysates

WB Recommended dilution:

200-1000