兔抗HSD17B2多克隆抗体

Background:

17β-HSD2 (17β hydroxysteroid dehydrogenase type 2) belongs to the 17β-HSD family of proteins that regulate the availability of steroids within a tissue. 17β-HSD2 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and testosterone. Due to the affects that 17β-HSD2 has on the availability of estrogen, it has been extensively investigated for playing a possible role in breast tumor development, colon cancer development and the pathophysiology of endometriosis.

Applications:

ELISA, WB, IHC

Name of antibody:

HSD17B2

Immunogen:

Fusion protein of human HSD17B2

Full name:

hydroxysteroid (17-beta) dehydrogenase 2

Synonyms：

HSD17; SDR9C2; EDH17B2

SwissProt:

P37059

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human esophagus cancer and human brain

IHC Recommend dilution:

50-200

WB Predicted band size:

43 kDa

WB Positive control:

Human fetal liver tissue

WB Recommended dilution:

500-2000