小鼠抗MLF2单克隆抗体

Background:

Myeloid leukemia factor (MLF) proteins typically demonstrate highest levels of expression in testis, ovary, skeletal muscle, heart, kidney and colon tissues, and lower levels of expression in spleen, thymus, and peripheral blood leukocytes. MLF proteins play a role in normal hemopoietic differentiation as well as in erythroid/myeloid lineage switching. MLF2 is a ubiquitously expressed, 248-amino acid protein which shares 40% sequence identity with myeloid leukemia factor 1 (MLF1). MLF2 maps to chromosome 12p13, a region that is often associated with translocations in acute leukemias of lymphoid and myeloid origin. However, no alterations in the structure of the MLF2 locus in patients shown to have 12p translocations have been discovered.

Applications:

WB, IHC

Name of antibody:

MLF2

Immunogen:

Fusion protein of human MLF2

Full name:

myeloid leukemia factor 2 (MLF2), transcript variant 1

Synonyms:

NTN4

SwissProt:

Q15773

IHC positive control:

carcinoma of human lung tissue and adenocarcinoma of human ovary tissue; human pancreas tissue and adenocarcinoma of human endometrium tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

28 kDa

WB Positive control:

Hela, SVT2, A549, COS7, Jurkat, MCF7 cell lysates

WB Recommended dilution:

200-1000