小鼠抗HABP2单克隆抗体

Background:

This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by hepatocytes and proteolytically processed to generate heavy and light chains that form the mature heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This extracellular protease binds hyaluronic acid and may play a role in the coagulation and fibrinolysis systems. Mutations in this gene are associated with nonmedullary thyroid cancer and susceptibility to venous thromboembolism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

Applications:

WB, IHC

Name of antibody:

HABP2

Immunogen:

Fusion protein of human HABP2

Full name:

hyaluronan binding protein 2

Synonyms:

FSAP; HABP; PHBP; HGFAL; NMTC5

SwissProt:

Q14520

IHC positive control:

Human breast tissue

IHC Recommend dilution:

500-2000

WB Predicted band size:

63 KD

WB Positive control:

HepG2, MCF7 and A549 cell lysates

WB Recommended dilution:

200-1000