兔抗ITGA2B多克隆抗体

Background:

ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Applications:

ELISA, WB, IHC

Name of antibody:

ITGA2B

Immunogen:

Fusion protein of human ITGA2B

Full name:

integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

Synonyms：

GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16

SwissProt:

P08514

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human colon cancer and human lung cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

113 kDa

WB Positive control:

Human fetal liver and placenta tissue

WB Recommended dilution:

200-1000